Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Pecam1  platelet/endothelial cell adhesion molecule 1   (Synonyms: Cd31, PECAM-1)
Results	Reference
1	J:320761 Abe S, Murashima A, Kimura E, Ema M, Hitomi J, Early development of the pulmonary vascular system: An anatomical and histochemical reinvestigation of the pulmonary venous return development in mice. Acta Histochem. 2022 Feb;124(2):151840
1	J:53085 Adams RH, Wilkinson GA, Weiss C, Diella F, Gale NW, Deutsch U, Risau W, Klein R, Roles of ephrinB ligands and EphB receptors in cardiovascular development: demarcation of arterial/venous domains, vascular morphogenesis, and sprouting angiogenesis. Genes Dev. 1999 Feb 1;13(3):295-306
1*	J:36690 Buck CA, Edelman JM, Buck CE, Kennedy G, Baldwin HS, Expression patterns of adhesion receptors in the developing mouse lung: functional implications. Cell Adhes Commun. 1996 Aug;4(2):69-87
1*	J:334839 Chuang CK, Chen SF, Su YH, Chen WH, Lin WM, Wang IC, Shyue SK, The Role of SCL Isoforms in Embryonic Hematopoiesis. Int J Mol Sci. 2023 Mar 29;24(7)
1	J:57908 Gerety SS, Wang HU, Chen ZF, Anderson DJ, Symmetrical mutant phenotypes of the receptor EphB4 and its specific transmembrane ligand ephrin-B2 in cardiovascular development. Mol Cell. 1999 Sep;4(3):403-14
1	J:325252 Hou S, Li Z, Dong J, Gao Y, Chang Z, Ding X, Li S, Li Y, Zeng Y, Xin Q, Wang B, Ni Y, Ning X, Hu Y, Fan X, Hou Y, Li X, Wen L, Zhou B, Liu B, Tang F, Lan Y, Heterogeneity in endothelial cells and widespread venous arterialization during early vascular development in mammals. Cell Res. 2022 Apr;32(4):333-348
1	J:119566 Ishimura A, Ng JK, Taira M, Young SG, Osada S, Man1, an inner nuclear membrane protein, regulates vascular remodeling by modulating transforming growth factor beta signaling. Development. 2006 Oct;133(19):3919-28
1	J:272613 Koutelou E, Wang L, Schibler AC, Chao HP, Kuang X, Lin K, Lu Y, Shen J, Jeter CR, Salinger A, Wilson M, Chen YC, Atanassov BS, Tang DG, Dent SYR, USP22 controls multiple signaling pathways that are essential for vasculature formation in the mouse placenta. Development. 2019 Feb 22;146(4):dev174037
1	J:226395 Lewis AE, Hwa J, Wang R, Soriano P, Bush JO, Neural crest defects in ephrin-B2 mutant mice are non-autonomous and originate from defects in the vasculature. Dev Biol. 2015 Oct 15;406(2):186-95
1*	J:198274 Mikelis CM, Palmby TR, Simaan M, Li W, Szabo R, Lyons R, Martin D, Yagi H, Fukuhara S, Chikumi H, Galisteo R, Mukouyama YS, Bugge TH, Gutkind JS, PDZ-RhoGEF and LARG are essential for embryonic development and provide a link between thrombin and LPA receptors and Rho activation. J Biol Chem. 2013 Apr 26;288(17):12232-43
1	J:344834 Ning X, Du J, Gong Y, Yao Y, Bai Z, Ni Y, Li Y, Li Z, Zhao H, Zhou J, Liu B, Lan Y, Hou S, Divergent expression of Neurl3 from hemogenic endothelial cells to hematopoietic stem progenitor cells during development. J Genet Genomics. 2023 Sep;50(9):661-675
1	J:229464 Rana U, Liu Z, Kumar SN, Zhao B, Hu W, Bordas M, Cossette S, Szabo S, Foeckler J, Weiler H, Chrzanowska-Wodnicka M, Holtz ML, Misra RP, Salato V, North PE, Ramchandran R, Miao QR, Nogo-B receptor deficiency causes cerebral vasculature defects during embryonic development in mice. Dev Biol. 2016 Feb 15;410(2):190-201
1	J:171522 Sandell LL, Iulianella A, Melton KR, Lynn M, Walker M, Inman KE, Bhatt S, Leroux-Berger M, Crawford M, Jones NC, Dennis JF, Trainor PA, A phenotype-driven ENU mutagenesis screen identifies novel alleles with functional roles in early mouse craniofacial development. Genesis. 2011 Apr;49(4):342-59
1*	J:119668 Sirois J, Cote JF, Charest A, Uetani N, Bourdeau A, Duncan SA, Daniels E, Tremblay ML, Essential function of PTP-PEST during mouse embryonic vascularization, mesenchyme formation, neurogenesis and early liver development. Mech Dev. 2006 Dec;123(12):869-80
1*	J:80044 Sohn SJ, Sarvis BK, Cado D, Winoto A, ERK5 MAPK regulates embryonic angiogenesis and acts as a hypoxia-sensitive repressor of vascular endothelial growth factor expression. J Biol Chem. 2002 Nov 8;277(45):43344-51
1	J:132583 Stankunas K, Hang CT, Tsun ZY, Chen H, Lee NV, Wu JI, Shang C, Bayle JH, Shou W, Iruela-Arispe ML, Chang CP, Endocardial Brg1 represses ADAMTS1 to maintain the microenvironment for myocardial morphogenesis. Dev Cell. 2008 Feb;14(2):298-311
1*	J:37459 Suri C, Jones PF, Patan S, Bartunkova S, Maisonpierre PC, Davis S, Sato TN, Yancopoulos GD, Requisite role of angiopoietin-1, a ligand for the TIE2 receptor, during embryonic angiogenesis. Cell. 1996 Dec 27;87(7):1171-80
1	J:222828 Tessneer KL, Pasula S, Cai X, Dong Y, McManus J, Liu X, Yu L, Hahn S, Chang B, Chen Y, Griffin C, Xia L, Adams RH, Chen H, Genetic reduction of vascular endothelial growth factor receptor 2 rescues aberrant angiogenesis caused by epsin deficiency. Arterioscler Thromb Vasc Biol. 2014 Feb;34(2):331-7
1	J:140124 Walls JR, Coultas L, Rossant J, Henkelman RM, Three-dimensional analysis of vascular development in the mouse embryo. PLoS One. 2008;3(8):e2853
1	J:75288 Wang HU, Chen ZF, Anderson DJ, Molecular distinction and angiogenic interaction between embryonic arteries and veins revealed by ephrin-B2 and its receptor Eph-B4. Cell. 1998 May 29;93(5):741-53
1	J:238547 Wang X, Chen D, Chen K, Jubran A, Ramirez A, Astrof S, Endothelium in the pharyngeal arches 3, 4 and 6 is derived from the second heart field. Dev Biol. 2017 Jan 15;421(2):108-117
1	J:107620 Yan L, Carr J, Ashby PR, Murry-Tait V, Thompson C, Arthur JS, Knockout of ERK5 causes multiple defects in placental and embryonic development. BMC Dev Biol. 2003 Dec 16;3:11
1*	J:60748 Yang J, Boerm M, McCarty M, Bucana C, Fidler IJ, Zhuang Y, Su B, Mekk3 is essential for early embryonic cardiovascular development. Nat Genet. 2000 Mar;24(3):309-13
1	J:326087 Yang Y, Mumau M, Tober J, Zhu Q, Bennett L, Hong C, Sung D, Keller T, Uzun Y, Gao P, Shewale S, Chen M, Yang J, Chen X, Thomas SA, Tan K, Speck NA, Kahn ML, Endothelial MEKK3-KLF2/4 signaling integrates inflammatory and hemodynamic signals during definitive hematopoiesis. Blood. 2022 May 12;139(19):2942-2957
1	J:165571 Yokomizo T, Dzierzak E, Three-dimensional cartography of hematopoietic clusters in the vasculature of whole mouse embryos. Development. 2010 Nov;137(21):3651-61
1	J:174699 Yokomizo T, Ng CE, Osato M, Dzierzak E, Three-dimensional imaging of whole midgestation murine embryos shows an intravascular localization for all hematopoietic clusters. Blood. 2011 Jun 9;117(23):6132-4
1*	J:235365 Yzaguirre AD, Speck NA, Insights into blood cell formation from hemogenic endothelium in lesser-known anatomic sites. Dev Dyn. 2016 Oct;245(10):1011-28